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Lei Wang, PhD

Assistant Professor in Psychiatry and Behavioral Sciences and Radiology

Contact

leiwang1@northwestern.edu
312-503-3983
312-503-3981
Abbott Hall Suite 1322
710 N Lake Shore Drive
Chicago IL 60611

Web Site Link

http://niacal.northwestern.edu

Affiliated Centers

Research Collaborators

Learn more about Lei Wang's research collaboration network

Interests

Aging; Alzheimer's Disease; Bioengineering; Bioinformatics; Psychiatry; Psychology; Radiology; Schizophrenia

Description of Interests

Dr. Lei Wang's lab research is focused on the development of multidimensional and multimodal neuroimaging biomarkers using the tools of computational anatomy. Working with collaborators from engineering, mathematics, psychology and clinical specialties, the team focuses on the following major areas: Mapping of Brain Structures using MRI. Dr. Wang develops automated pipelines to delineate brain structures based on simultaneous mappings of multiple structures from multiple atlases. This includes deep brain structures (such as the hippocampus, amygdala, thalamus, and basal ganglia) and cortical structures.Complex Neuroimaging Biomarkers. They develop modeling and statistical approaches for the analysis of these maps and frameworks for joint, integrated analyses of multidimensional, multimodal information based on the structural mapping of the brain. These include: • Multimodal MRI analysis: structural MRI, functional MRI, diffusion MRI, perfusion MRI, PET • Network analysis • Structure-function relationship • Subtyping and dimensional analysis • Prediction and longitudinal analysis Clinical Applications We are interested in developing neuroimaging markers to characterize neuropsychiatric disorders, disease progression and prediction, and monitoring of treatment:
• Mild cognitive impairment (MCI), dementia • Breast cancer-related MCI • Psychosis/Schizophrenia/Mood Disorders • Imaging Genetics Neuroinformatics • Data sharing • Data mediation Preclinical Applications Neuroimaging of Animal Models • Schizophrenia, Dementia, Mood Disorders, Memory • Mouse, rat, rabbit

Professional Education

PhD: Harvard University (1995)

Most Recent Publications

Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME, Bauer M, Bearden CE, Bergmann O, Binder EB, Blangero J, Bockholt HJ, Bøen E, Bois C, Boomsma DI, Booth T, Bowman IJ, Bralten J, Brouwer RM, Brunner HG, Brohawn DG, Buckner RL, Buitelaar J, Bulayeva K, Bustillo JR, Calhoun VD, Cannon DM, Cantor RM, Carless MA, Caseras X, Cavalleri GL, Chakravarty MM, Chang KD, Ching CRK, Christoforou A, Cichon S, Clark VP, Conrod P, Coppola G, Crespo-Facorro B, Curran JE, Czisch M, Deary IJ, de Geus EJC, den Braber A, Delvecchio G, Depondt C, de Haan L, de Zubicaray GI, Dima D, Dimitrova R, Djurovic S, Dong H, Donohoe G, Duggirala R, Dyer TD, Ehrlich S, Ekman CJ, Elvsåshagen T, Emsell L, Erk S, Espeseth T, Fagerness J, Fears S, Fedko I, Fernández G, Fisher SE, Foroud T, Fox PT, Francks C, Frangou S, Frey EM, Frodl T, Frouin V, Garavan H, Giddaluru S, Glahn DC, Godlewska B, Goldstein RZ, Gollub RL, Grabe HJ, Grimm O, Gruber O, Guadalupe T, Gur RE, Gur RC, Göring HHH, Hagenaars S, Hajek T, Hall GB, Hall J, Hardy J, Hartman CA, Hass J, Hatton SN, Haukvik UK, Hegenscheid K, Heinz A, Hickie IB, Ho B-C, Hoehn D, Hoekstra PJ, Hollinshead M, Holmes AJ, Homuth G, Hoogman M, Hong LE, Hosten N, Hottenga J-J, Hulshoff Pol HE, Hwang KS, Jack Jr. CR, Jenkinson M, Johnston C, Jönsson EG, Kahn RS, Kasperaviciute D, Kelly S, Kim S, Kochunov P, Koenders L, Krämer B, Kwok JBJ, Lagopoulos J, Laje G, Landen M, Landman BA, Lauriello J, Lawrie SM, Lee PH, Le Hellard S, Lemaître H, Leonardo CD, Li C-s, Liberg B, Liewald DC, Liu X, Lopez LM, Loth E, Lourdusamy A, Luciano M, Macciardi F, Machielsen MWJ, MacQueen GM, Malt UF, Mandl R, Manoach DS, Martinot J-L, Matarin M, Mather KA, Mattheisen M, Mattingsdal M, Meyer-Lindenberg A, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meisenzahl E, Melle I, Milaneschi Y, Mohnke S, Montgomery GW, Morris DW, Moses EK, Mueller BA, Muñoz Maniega S, Mühleisen TW, Müller-Myhsok B, Mwangi B, Nauck M, Nho K, Nichols TE, Nilsson L-G, Nugent AC, Nyberg L, Olvera RL, Oosterlaan J, Ophoff RA, Pandolfo M, Papalampropoulou-Tsiridou M, Papmeyer M, Paus T, Pausova Z, Pearlson GD, Penninx BW, Peterson CP, Pfennig A, Phillips M, Pike GB, Poline J-B, Potkin SG, Pütz B, Ramasamy A, Rasmussen J, Rietschel M, Rijpkema M, Risacher SL, Roffman JL, Roiz-Santiañez R, Romanczuk-Seiferth N, Rose EJ, Royle NA, Rujescu D, Ryten M, Sachdev PS, Salami A, Satterthwaite TD, Savitz J, Saykin AJ, Scanlon C, Schmaal L, Schnack HG, Schork AJ, Schulz SC, Schür R, Seidman L, Shen L, Shoemaker JM, Simmons A, Sisodiya SM, Smith C, Smoller JW, Soares JC, Sponheim SR, Sprooten E, Starr JM, Steen VM, Strakowski S, Strike L, Sussmann J, Sämann PG, Teumer A, Toga AW, Tordesillas-Gutierrez D, Trabzuni D, Trost S, Turner J, Van den Heuvel M, van der Wee NJ, van Eijk K, van Erp TGM, van Haren NEM, van 't Ent D, van Tol M-J, Valdés Hernández MC, Veltman DJ, Versace A, Völzke H, Walker R, Walter H, Wang L, Wardlaw JM, Weale ME, Weiner MW, Wen W, Westlye LT, Whalley HC, Whelan CD, White T, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Zilles D, Zwiers MP, Thalamuthu A, Schofield PR, Freimer NB, Lawrence NS, Drevets W.
Brain Imaging and Behavior. 2014 Jan;1-30.doi:10.1007/s11682-013-9269-5.
ISSN: 19317557

Takayanagi M, Wentz J, Takayanagi Y, Schretlen DJ, Ceyhan E, Wang L, Suzuki M, Sawa A, Barta PE, Ratnanather JT, Cascella NG.
Schizophrenia Research. 2013 Nov;150(2-3):484-490.doi:10.1016/j.schres.2013.07.036.
PMID: 24035178   ISSN: 09209964

Beg MF, Raamana PR, Barbieri S, Wang L.
Statistical Methods in Medical Research. 2013 Aug;22(4):439-462.doi:10.1177/0962280212448975.
PMID: 22653846   ISSN: 09622802

Johnson SLM, Wang L, Alpert KI, Greenstein D, Clasen L, Lalonde F, Miller R, Rapoport J, Gogtay N.
Journal of the American Academy of Child and Adolescent Psychiatry. 2013 May;52(5):527-536.e2.doi:10.1016/j.jaac.2013.02.003.
PMID: 23622854   ISSN: 08908567


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