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Lee E Miller

Lee E Miller, PhD

Professor in Physiology/Physical Medicine and Rehabilitation


Ward Building Room 5-315
303 E Chicago Avenue
Chicago IL 60611

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Movement Control; Neural Engineering; Neuroscience; Spinal Cord Injury

Description of Interests

The three fundamental goals of my research are the following: 1) To understand the nature of the brain's own signals -- the "language" in which movement commands are expressed by neurons in the central nervous system. 2) To understand the mechanisms by which these signals are produced -- the nature of the connections among networks of neurons, and the transformations that occur in the signals as they propagate throughout these networks. 3) To develop applications of these basic principles that could be of therapeutic value to human patients. Much of this work is done in collaboration with students and faculty from the Biomedical Engineering Department and the Interdepartmental Neuroscience Program (NUIN).

Professional Education

PhD: Northwestern University, Physiology (1990)
Postdoctoral Fellowship: University of Nijmegen (1992)

Most Recent Publications

Bensmaia SJ, Miller LE.
Nature Reviews Neuroscience. 2014 Jan;15(5):313-325.doi:10.1038/nrn3724.
PMID: 24739786   ISSN: 1471003X

Zaaimi B, Ruiz-Torres R, Solla SA, Miller LE.
Journal of Neural Engineering. 2013 Oct;10(5):doi:10.1088/1741-2560/10/5/056013.
PMID: 23985904   PMCID: PMC3821924   ISSN: 17412560

Cherian A, Ernandes HL, Miller LE.
Journal of Neurophysiology. 2013 Aug;110(3):768-783.doi:10.1152/jn.00109.2012.
PMID: 23657285   PMCID: PMC3742991   ISSN: 00223077

Ledbetter NM, Ethier C, Oby ER, Hiatt SD, Wilder AM, Ko JH, Agnew SP, Miller LE, Clark GA.
Journal of Neurophysiology. 2013 Jan 15;109(2):580-590.doi:10.1152/jn.00688.2011.
PMID: 23076108   PMCID: PMC3545468   ISSN: 00223077

Selected Books and Book Chapters

Oby ER, Ethier C, Bauman M, Perreault EJ, KO J, Miller LE. Prediction of Muscle Activity from Cortical Signals to Restore Hand Grasp in Subjects with Spinal Cord Injury.. In: O'Weiss KG. 2010. Statistical Signal Processing for Neuroscience and Neurotechnology.. New York: Academic Press, Elsevier

Miller LE, Gibson A. The Red Nucleus.. In: Squire L. 2009. Encyclopedia of Neuroscience.. Oxford: Academic Press 55-62.

Mussa-Ivaldi FA, Miller LE, Rymer WZ, Weir RF. Neural Engineering.. In: Parasuraman R, Rizzo M. 2007. Neuroergonomics: The Brain at Work.. Oxford: Oxford University Press 293-312.

Houk JC, Miller LE. Cerebellum: Movement regulation and cognitive functions.. In: Macmillan. 2001. Encyclopedia of Life Sciences. New York: Macmillan

View all 103 publications

External Professional Relationships

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Northwestern University Feinberg School of Medicine
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